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Which PD patients will you be implementing tavapadon?

2 Answers
Mednet Member
Mednet Member
Neurology · Keck School of Medicine of USC

I am excited to try this new selective D1/D5 dopamine agonist to address mild-to-moderate motor symptoms of Parkinson's disease and wearing off/motor fluctuations. Being a selective agonist at D1/D5 receptors, tavapadon has the potential for fewer side effects, such as drowsiness, nausea, and impuls...

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Mednet Member
Mednet Member
Neurology · Beth Israel Deaconess Medical Center

Tavapadon, a selective D1/D5 partial agonist, demonstrated efficacy in two distinct PD populations across three Phase 3 TEMPO trials (Pahwa et al., PMID 41860533; Fernandez et al., PMID 42456682; Fernandez et al., PMID 41860544). It remains investigational and is not yet FDA-approved, but the clinic...

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