Do you consider testing and treating IDA in unexplained thrombocytopenia?
I read that paper and was not convinced, but it was surely interesting. In reality, an enormously more likely platelet event with iron deficiency is a reactive thrombocytosis. Iron deficiency can occur in the extremely unlikely event of excess bleeding with thrombocytopenia, but as an epiphenomenon ...
I do consider testing iron studies in patients with unexplained thrombocytopenia. It's certainly not the most common hematologic manifestation of severe iron deficiency (and in fact thrombocytosis from iron deficiency is much more common), but it has been reported in the attached paper as well as in...
Iron deficiency often causes thrombocytosis, and in fact probably is the most common cause of reactive thrombocytosis encountered in clinic practice.
With very severe iron deficiency, thrombocytopenia can be seen. I have seen it in rare patients presenting with hemoglobin levels about 3 gm/dL or less...