Are you more likely to use cefazolin over antistaphylococcal penicillins for MSSA bacteremia in light of the recent publication of the SNAP trial?

I had already mostly transitioned to using cefazolin; while I occasionally use oxacillin for CRRT patients, I have found that oxacillin is a very difficult drug for patients to tolerate (in my experience), with AIN happening with relatively alarming frequency considering how infrequently I use it. A...

You nailed it. At our institution, cefazolin is our preferred IV antibiotic for MSSA bacteremia. Based on SNAP and a variety of other studies, we know that beta-lactams are more effective than vancomycin. Moreover, cefazolin is better tolerated than antistaphylococcal penicillins, while also being e...