Mednet Logo
HomeQuestion

Do you think we can extrapolate the results of TOGETHER-PsA and expect similar results and safety when adding Tirzepatide to another IL-17 inhibitor or to a bDMARD with different mechanism of action?

1
2 Answers
Mednet Member
Mednet Member
Rheumatology · University of Rochester

Yes and no. We don't have hard randomized controlled trial (RCT) data with biologic disease-modifying antirheumatic drugs (bDMARDs) other than ixekizumab at present. However, if we extrapolate data from prior weight loss studies in psoriatic arthritis (PsA) and psoriasis (PsO), it would be reasonabl...

Register or Sign In to see full answer

Mednet Member
Mednet Member
Rheumatology · University of Rochester Medical Center

Yes. An abstract presented at the recent EULAR meeting showed the efficacy and safety of GLP-1 agents in combination with other biologics, using a propensity-matched retrospective control group (Venerito et al., EULAR 2026).

Register or Sign In to see full answer