How would you manage a child with subtotal resection of an atypical choroid plexus papilloma?
2 Answers
Mednet Member
Pediatric Hematology/Oncology · C. S. Mott Children’s Hospital, University of Michigan
Data from the SickKids Hospital study strongly suggest that the extent of resection is prognostic in atypical CPP, and in the presence of GTR, chemotherapy may be avoided or skipped entirely (Browne-Farmer et al., PMID 34529227). The role of adjuvant treatment in the setting of incompletely resected...
Mednet Member
Pediatric Hematology/Oncology · University of Toronto Faculty of Medicine
I agree with Santhosh. There are anecdotal cases of transformation into CPC, and staining for p53 is recommended. Otherwise, observation is an option. Of course, if the surgeon feels that he/she can resect the residual, this is the first and best option. I agree that the role of chemotherapy is stil...