Are there any clinical situations in which checking for anti-chromatin antibodies is helpful?
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1 Answers
Mednet Member
Rheumatology · Georgetown University Hospital
Chromatin is the native complex of histones and DNA found in the cell nucleus of eukaryotes. The prevalence of anti-chromatin (nucleosome) antibodies in systemic lupus erythematosus (SLE) varies from 50% to 90%, being similar to that of the historic LE cell.
The question is whether this provides addi...