Dermatology
Clinical insights on skin conditions, dermatologic procedures, and treatment approaches from practicing dermatologists.
Recent Discussions
How do you approach the timing of skin tightening interventions in patients who experience significant weight loss to optimize both intermediate and long-term aesthetic outcomes?
I like PLLA to add natural-looking volume and use HA fillers for areas not suitable for PLLA.
How have you used GLP1s in dermatology?
No, not yet.
Should ertapenem use in refractory HS be managed by ID, and how many times would you consider using it in a patient?
I wish that infectious disease would manage severe hidradenitis suppurativa with IV ertapenem. In my experience, ID is typically reluctant to use ertapenem. I can understand that they are thinking about antibiotic stewardship and maintaining the utility of this broad-spectrum antibiotic. When I have...
At what age are you comfortable to start prescribing spironolactone for acne in adolescent females?
When I first reported the utility of spironolactone in women, I was concerned about possible development issues,in young women particularly muscle development which is influenced by androgens. After consulting with pediatric endocrinologist colleagues at Children's Hospital Philadelphia who saw no c...
What treatment and management recommendations do you have for amphetamine-induced skin picking disorder without insight?
Assuming the stimulant is prescribed for ADHD, I recommend dose reduction or switching to a different medication, or, rarely, I recommend the patient consider a "stimulant holiday" for at least 1-2 months. I explain that most of my patients notice improvement with adjustments or breaks from their st...
How do you use transexamic acid (TXA) during dermatologic procedures?
I personally use it topically, but others have used subcutaneous injections. When used topically, it has been easiest to soak a gauze/pad in the TXA and place it directly on the defect, as described in the reference below. Otherwise, it can be injected directly (subcutaneously) into the wound, inclu...
Do you find that hydroxyzine worsens cognitive symptoms in patients who are already susceptible to cognitive impairment?
Hydroxyzine should not have a direct negative effect on cognition. For decades after its inception, it was lopped in with Benadryl in terms of its receptor binding affinity profile and is listed in several anticholinergic burden scales as being anticholinergic. Similar to the child’s game ‘telephone...
In older male patients with a history of underlying autoimmune disease, what clinical manifestations would prompt you to evaluate for VEXAS Syndrome?
Hello!!!Skin lesions, elevated MCV, elevated inflammatory markers.
Have you had success in treating extensive lichen nitidus with a systemic therapy?
I have never attempted to treat lichen nitidus with systemic therapy, as most patients are largely asymptomatic, and we know it is typically a self-limited condition.
What is your approach to patients with SLE who develop a rash after hydroxychloroquine initiation?
First, I diagnose the type of rash. If it is a severe cutaneous reaction, e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), or if it is a more persistent type of reaction like a lichenoid reaction, I stop hydroxychlor...