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Dermatology

Clinical insights on skin conditions, dermatologic procedures, and treatment approaches from practicing dermatologists.

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How do you utilize JAK inhibitors in combination with other therapies to manage alopecia?

1 Answers

Mednet Member
Mednet Member
Dermatology · Mount Sinai

In general, JAK inhibitors can be considered a first-line treatment for many patients with severe alopecia areata, so they are often the primary treatment that I use for this condition. In almost all patients, however, I also add oral minoxidil to the treatment regimen (depending on the person, typi...

What is your approach to treating genital lichen sclerosus that is not responding to super-potent topical steroids?

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1 Answers

Mednet Member
Mednet Member
Dermatology · Forefront Dermatology

Biopsy is the next step if it was never done to rule out SCC or another alternative process since clobetasol typically works in these cases. Traditionally, methotrexate has been a standard treatment. However, more recently, I've started using Rinvoq off-label with great efficacy.

What treatment modalities have you had success in treating perioral or periorbital dermatitis when they have failed Topical calcineurin inhibitor and oral antibiotics?

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2 Answers

Mednet Member
Mednet Member
Dermatology · Duke Health

The first line is typically metronidazole and/or clindamycin. Topical ivermectin is also a very reasonable approach, and sulfacetamide can help as well. I typically use these before topical calcineurin inhibitors. Rarely TCIs can worsen demodex as has been reported. Which oral antibiotics? Doxycycli...

What's your treatment algorithm for notalgia paresthetica?

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2 Answers

Mednet Member
Mednet Member
Dermatology · Forefront Dermatology

Topical steroids + dermeleve (otc anti-pruritic) cream ILK versus other OTC topicals (capsaicin, Sarna, pramoxine) versus compounded gabapentin, amitriptyline, lidocaine (my main go-to second line) Oral - gabapentin vs doxepin vs desipramine Recalcitrant cases I’ve added dupilumab or phototherapy w...