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Geriatric Medicine

Geriatric Medicine

Physician insights on aging-related care, polypharmacy management, cognitive decline, and geriatric syndromes.

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What are some practical tips in distinguishing between metabolic bone disease due to chronic kidney disease and osteoporosis?

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Nephrology · U Chicago

The biggest difference between osteoporosis and CKD-MBD has to do with the underlying bone mineral laboratories. Generally, with osteoporosis, bone chemistries are relatively normal; there may be a decrease in Vit D. However, with CKD-MBD, there is usually an increase in PTH, potentially abnormaliti...

Does global brain atrophy increase risk for intracranial bleed after fall in older adults?

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Neurology · Vanderbilt University Medical Center

It depends on the location of the hemorrhage. Subdural bleeding/hematoma is much more likely in elderly people with brain atrophy and a fall. Epidural hemorrhage is much more common in young patients. Intracerebral hemorrhage is more related to risk factors such as hypertension in middle age and amy...

What is your approach to picking a dose/formulation of Vitamin D for a community-dwelling older adult found to have Vitamin D deficiency?

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Geriatric Medicine · University of California San Francisco

Supplementation with cholecalciferol (vitamin D3) 1000–2000 IU daily would be my choice for community-dwelling older adults with documented deficiency, and is preferred over ergocalciferol (vitamin D2). I would also co-administer calcium (1000–1200 mg/day) to support fracture prevention. Routine lab...

What is your approach to antibiotic selection for bacterial species that demonstrate susceptibility to penicillins or cephalosporins on testing, but are known to harbor inducible AmpC resistance?

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Infectious Disease · Christiana Care Health Syst

I will assess how long I am treating the person/infection, and go from there in terms of how likely I am to induce the AmpC based on the duration of treatment. For example, if it's a 7-day course for UTI or GN bacteremia, I may risk the penicillin/cephalosporin (based on susceptibilities, of course)...

In an older adults with dementia-related behavioral symptoms refractory to nonpharmacological management in whom you are starting SSRI, do you ever consider a short course of antipsychotic medication to overlap with the initiation of SSRI while waiting for therapeutic effect?

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Geriatric Medicine · Beth Israel Deaconess Medical Center

The American Geriatric Society recommends that antipsychotics may be considered when behaviors do not respond to non-pharmacological management and the patient is at risk of harming themselves or others. Thereby, it may be reasonable to overlap short-term antipsychotic with SSRI initiation in older ...

In an older adult hospitalized with recurrent falls, weight loss, without clear injuries, but with an inconsistent or difficult-to-reach caregiver, what findings would make you formally report suspected elder neglect and/or abuse?

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Geriatric Medicine · Keck Hospital of USC

I'm so glad that you're thinking about the possibility of abuse/neglect in this scenario! It's important to have it on our differential, or we'll always miss this diagnosis. First, it would be good to see if the patient can explain what is happening and provide contextual information that veers us a...

What is your approach to the use of GLP-1 agonists in older adults with diabetes with or at risk of sarcopenia?

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Geriatric Medicine · University of California, San Francisco

This is an important question to keep an eye on, given the broadening use and effectiveness of GLP-1 agonists for various conditions, especially diabetes, and for weight loss. Unfortunately, as is so often the case, major clinical trials in this area do not reflect the heterogeneity of older adults ...

In light of recent measles outbreaks in the US, would you recommend an MMR booster for immunocompetent patients born before 1957?

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Infectious Disease · Perelman School of Medicine at the University of Pennsylvania

I would not recommend a measles vaccine for a person born before 1957. This year has been chosen because people before born before 1957 have a very very high likelihood of having had measles because virtually all children got this highly contagious disease. On the other hand, there is no harm to get...

What are your thoughts about lion's mane supplementation to slow the decline or improve cognitive capacity for those at risk of dementia?

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Geriatric Medicine · Wake Forest University School of Medicine

Lion's mane is the latest in the ever-evolving list of supplements that have a whiff of animal data, very small human trials, or frankly, anecdotal evidence. A decade ago, it was coconut oil; last week, it was lithium. There will always be suggestions of the benefit of this or that. Currently, there...

How do you counsel older adults regarding the use, dosing, and safety of CBD-containing products for insomnia?

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Geriatric Medicine · David Geffen School of Medicine at UCLA

When counseling older adults on CBD use for insomnia, I usually explain that evidence for safety and effectiveness is limited. Most products are not FDA-approved, and their labeling, purity, and dosing can be inconsistent. It’s important to review the patient’s comorbidities and medications closely,...