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Physician discussions on inpatient care, transitions of care, diagnostic reasoning, and hospital-based protocols.

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Do you utilize soluble IL-2 receptor or ACE levels as serum biomarkers to monitor disease activity in pulmonary sarcoidosis?

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Pulmonology · Thomas Jefferson University Hospitals

I use ACE levels to monitor disease activity in patients who demonstrate elevated ACE levels at diagnosis of confirmed sarcoidosis and for which there is no other explanation for elevation of ACE. ACE normalizes with treatment and will increase again if/when the disease relapses. The literature indi...

How does the presence of gallbladder sludge vs stones on POCUS impact your suspicion for gallbladder disease as a cause of abdominal pain?

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Hospital Medicine · Oregon Health and Science University Hospital

With all point-of-care ultrasound, so much depends on your pre-test probability before you acquire the image. If you are simply trying to identify biliary colic in a patient with a good history of the disease, then the presence of either sludge or stones is quite an effective test with bedside provi...

Under what circumstances do you recommend POCUS guidance for lumbar puncture?

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Hospital Medicine · Weill Cornell Medicine

If the circumstances allow for it, I would use ultrasound for guidance for LP every time a LP is performed. This allows for continued practice in identification of the landmarks and improves accuracy in POCUS when it's truly needed, as in obese patients, where landmarks are difficult to palpate. Got...

Under what circumstances do you recommend POCUS guidance for lumbar puncture?

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Hospital Medicine · Weill Cornell Medicine

If the circumstances allow for it, I would use ultrasound for guidance for LP every time a LP is performed. This allows for continued practice in identification of the landmarks and improves accuracy in POCUS when it's truly needed, as in obese patients, where landmarks are difficult to palpate. Got...

What are some TTE findings that suggest worsening function of a bioprosthetic AVR that would require further surveillance or diagnostic imaging?

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Cardiology · University of Texas Health Science Center at Houston

Doppler findings of an increasing transaortic gradient; 2D findings of decreased valve excursion and increased cusp calcification.

How exhaustive (especially considering cost) should an immunological workup be for patients with extensive, recurrent, or deep seated Staph aureus infections without obvious immunocompromise (e.g. cancer, diabetes, steroids) or recurrent breaks in skin integrity?

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Infectious Disease · Stanford Health Care

Obviously, children with recurrent Staph aureus infections should be evaluated for both CGD (chronic granulomatous disease) and IgM deficiency. However, the majority of adults with recurrent SA infections do not have a known systemic immunodeficiency. We should keep in mind that Staph aureus is an a...

How do you counsel patients on peritoneal dialysis regarding the safety of engaging in aerobic and resistance exercises, considering the risk of developing abdominal wall complications?

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Nephrology · UCHealth University of Colorado Hospital (UCH)

The effect of exercise on intra-abdominal pressure (IAP) while on PD was examined decades ago by Twardowski et al., PMID 3774076. They found that walking, jogging, or using an exercycle resulted in only modest increases in IAP, while jumping or straining (e.g. weight- lifting) resulted in more marke...

How would you approach surveillance imaging for men with early-stage, hormone receptor-positive breast cancer after unilateral mastectomy?

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Medical Oncology · Avita Health System

As always, appreciate others' input. If you're referring to systemic imaging, I do not obtain surveillance systemic imaging as part of surveillance for any patient with early-stage hormone-positive breast cancer (male or female) unless there are symptoms or initial labs that suggest possible metasta...

How do you approach the medical evaluation of new onset psychosis in elderly patients?

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Psychiatry · University of Washington

The medical evaluation of new-onset psychosis begins with a thorough history (medical, neurologic, and psychiatric history), including a history of the present illness, medications, as well as the use of alcohol and recreational drugs. Obtaining information from family or others who know the patient...

When do you send for genetic testing (e.g., SPINK1, PRSS1, CFTR) in a patient with recurrent or chronic pancreatitis without an obvious etiology and how does it impact your management?

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Gastroenterology · Stanford Medicine

I offer and discuss getting genetic testing in patients with idiopathic recurrent acute pancreatitis or chronic pancreatitis, more frequently in younger patients. Impact of testing can help identify undiagnosed CFTR patients, for whom further CF evaluation and management including options to try new...