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Medical Oncology

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Recent Discussions

Is there a role for low dose aspirin in a patient with AVN in four large joints who has underlying well-controlled SLE and positive APLs but no history of clots?

1 Answers

Mednet Member

Rheumatology · UT Southwestern Medical Center

AVN in SLE patients is common, most often in the context of glucocorticoid use. Thus, in this case, there is no evidence that APLAs are the etiology. Moreover, to the best of my knowledge, there is no evidence that primary prevention with aspirin in the setting of APLAs is effective. So I would not ...

What is the optimal management of a patient needing surgical clearance for a knee replacement with VWF Ag and factor VIII between 40-50 and no bleeding history?

1 Answers

Mednet Member

Hematology · University of Pittsburgh

This is a difficult question. I would make sure that the patients had adequate "stress tests" of their hemostatic system before concluding they have no bleeding history. For example, it is difficult to estimate the bleeding risk if somebody has never had surgery or pregnancy and has been on OCP sinc...

Medical Oncology

Recent Discussions

Is there a role for low dose aspirin in a patient with AVN in four large joints who has underlying well-controlled SLE and positive APLs but no history of clots?

What is the optimal management of a patient needing surgical clearance for a knee replacement with VWF Ag and factor VIII between 40-50 and no bleeding history?

Noelle K. LoConte, MD

Stephen V. Liu, MD

Sara M. Tolaney, MD, MPH

Lawrence H. Einhorn, MD

John C. Byrd, MD

Anthony Bejjani

Elizabeth Henry

John Baird