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What is your approach to counseling a patient with exertional hypoxia, but normal resting oxygen saturation, who is hesitant to use supplemental oxygen therapy?

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Pulmonology · Tufts Medical Center

Many of these patients are not only hesitant but actually reluctant. Considering that the hard evidence to support this application is weak at best, as long as the desaturation is transient, not associated with much in the way of symptoms, and bounces back fairly quickly when the exertion ceases, I ...

How do you manage patients with chemotherapy-induced paronychia?

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Dermatology · Loyola School of Medicine

I manage patients with chemotherapy-induced paronychia with a few tricks: First, ensure that there is no infection (active drainage, especially purulent) is more indicative of infection, as well as appropriate hygiene. Topical steroids and soothing soaks (such as Domeboro or diluted distilled white ...

Would you anticoagulate recurrent venous thromboembolism in a patient with Ehlers Danlos syndrome?

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Hematology · Mount Sinai

Yes, but know the hx of bleeding. Would use low dose Coumadin one 1.5 to 2, have good antidotes for Coumadin.

What are your recommendations for management of patients with familial polycythemia due to EPOR mutation during pregnancy?

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Hematology · Johns Hopkins University

This is not a question that has a definitive answer since I know of no reports dealing directly with this uncommon situation and I have never treated such a patient. I have, however, successfully treated many pregnant vera patients, who have a constitutively-active erythropoietin receptor (EPOR) due...

Do you escalate treatment for reactive lymphadenopathy in an otherwise stable and asymptomatic patient with lupus?

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Rheumatology · Uniformed Services University of the Health Sciences (USUHS)

With today's medical evidence, I do not treat my patients' lymphadenopathy (LAD) alone. However, lupus-reactive LAD tends to occur with active disease. I am a big believer in the treatment goal of "remission (without steroids); if remission is unachievable, then low disease activity using the safest...

Do you recommend routine genetic screening (i.e., periodic fever panel) in a pediatric patient where you strongly suspect a periodic fever syndrome?

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Rheumatology · Valley Children's Hospital

Genetic testing for periodic fever syndromes is potentially very informative and rather inexpensive. My approach is to generally obtain genetic testing in patients with suspected periodic fever syndromes as part of their initial laboratory evaluation with the exception of typical cases of PFAPA (Per...

How do you taper off Clonazepam in women with epilepsy who are family planning?

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Neurology · Orlando Health

Is she only on clonazepam and how much dose? Is she on additional AEDs and how many? Has she failed other AED and what are the other options I can add simultaneously while tapering off clonazepam? What type of epilepsy patient has? These are some of the considerations to keep in mind before switchi...

How do you manage patients with recurrent periorificial dermatitis?

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Dermatology · Froedtert & the Medical College of Wisconsin

I typically use oral doxycycline, whenever possible, and often the low subantimicrobial doses work as well as higher doses and are much more tolerable for patients. If they can't take antibiotics or prefer to avoid oral ones, I will use some combination of topical metronidazole, clindamycin, and top...

At what heart dose would you prospectively refer a patient to cardiology due to anticipated long term risks?

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Radiation Oncology · Allegheny Health Network, Pittsburgh

If a patient had prior BCT and now inflammatory, I would refer given the most likely plan for additional chemotherapy and RT. In general, I refer for cardiac oncology based on a combination of cardiac risk factors (HTN, DM, HLP), family cardiac history, anthracycline receipt, and cardiac dose (ex. I...

How do you approach urate-lowering therapy in patients with advanced chronic kidney disease?

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Rheumatology · Texas Tech University Health Sciences Center

I lower uric acid independent of GFR. There is little evidence to support limiting uric acid-lowering therapy. This misinformation came out due to combining fears that the incidence of allopurinol reactions would increase in patients with renal insufficiency. Allergic reactions are related to exposu...