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How do you counsel pregnant patients with myasthenia gravis?

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1 Answers

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Neurology · Northwestern Medicine

I generally discuss an action plan with female patients considering pregnancy, particularly emphasizing the importance of managing MG symptoms beforehand. Evidence indicates that patients under good control before pregnancy usually remain stable throughout. Treatment for MG during pregnancy typicall...

Do you use prednisone in the management of patients with persistent respiratory symptoms following acute COVID-19 infection?

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4 Answers

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Pulmonology · Gwinnett Pulmonary Group Lawrenceville

No, unless I note bronchial hyperresponsiveness on follow-up Pulmonary function tests (PFTs). What I've noted is a significantly high percentage of undiagnosed asthmatics who come into the light because of a more severe clinical course from covid. Use anti-fibrotics occasionally for fibrosis dependi...

How do you specifically counsel patients on conservative measures such as hand warming in the treatment of SSc associated digital ulceration?

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Rheumatology · Mayo Clinic

While Raynaud’s is nearly universal in Systemic sclerosis, digital ulcerations occur in approximately 30% of these patients yearly and tend to recur, with 2/3rd developing another one despite the use of vasodilators. Irreversible tissue loss, osteomyelitis, gangrene, and amputation are unfortunate c...

What screening recommendations do you provide for patients with a Nevus of Ota with ocular involvement?

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Dermatology · University of South Florida Morsani College of Medicine

Patients with Nevus of Ota are at increased risk of glaucoma. I have patients get a yearly ophthalmology exam.

How do you treat significant keloidal acne scarring on the back of a teenager?

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Dermatology · Central Dermatology Center

Firstly, their acne needs to be controlled and stable prior to treating the scars themselves unless any of the keloids are particularly symptomatic. My decision-making is shared with the patient and based on many different factors including skin type, pain tolerance, insurance coverage/budget, scar ...

What is your ferritin threshold to prescribe iron to female adolescent athletes who have symptomatic iron deficiency without anemia?

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Hematology · Georgetown University School of Medicine

Since ferritin should be truly reflective of iron levels as we should not expect elevated hepcidin levels in a young athlete. There, I would use 30 ng/mL which has a 98% specificity and 92% sensitivity for absent marrow hemosiderin. Also, since there is expected ongoing iron loss (0.6 mg/L of sweat ...

How do you approach treating nail lichen planus?

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Dermatology · Duke University

I would first start be determining the extent of cutaneous and mucosal involvement, as that often is more troublesome to the patient than the nails and may impact choice of treatment. Often, any systemic therapy directed at cutaneous/mucosal LP will also probably improve nail LP. Topical steroids to...

In a patient with APS and obesity during pregnancy when switched to LMWH, do you cap the dose of dalteparin as per manufacturers labeling at 18,000U per day or do you use weight based dosing?

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Hematology · Indiana Hemophilia and Thrombosis Center

Hi @Dr. First Last, We use enoxaparin in our institution, but the general principle that we follow is that we do not cap LMWH dose at a set threshold. I am assuming that you're referring to thromboprophylaxis and not the management of a VTE in the past 6 months. We monitor anti-Xa levels in obese p...

When do you recommend checking blink reflex in patients with Bell's Palsy?

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Neurology · University of Minnesota

I have personally found that blink reflex testing is not as important as emphasized in the literature for the cases of facial palsy that are referred to our Lab. This is because most facial nerve EMGs that we see, are severe cases with profound axonal injury that show poor recovery after 3-4 weeks. ...

How do you approach a patient with discordant breast cancer risk prediction scores for prevention?

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Medical Oncology · Ohio State University

It's not uncommon to come across discordant lifetime breast cancer risk estimates between routinely used risk assessment models such as Gail, TC V8.0, Claus, and CanRisk. These models differ widely in the risk elements, ability to incorporate results from germline panel testing/PRS, and their streng...