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Are drug challenges after serum sickness-like reactions useful in delabeling the allergy?

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1 Answers

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Allergy & Immunology · Long Island Allergy And Asthma

Too unpredictable each time.

Do you have to extend treatment for acute Lyme disease if a patient is on high dose steroids for another indication?

2 Answers

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Rheumatology · Berkshire Health Systems

I am unaware of any evidence to support longer-term therapy in such a setting. I am quite sure no such study has ever been done. Standard therapy for early Lyme disease is 10 days of appropriate antibiotics. Extending to 20 days would likely do no harm to the patient, but may not be necessary, and t...

Are you comfortable utilizing Stelara (ustekinumab) as biologic treatment of psoriasis for patients with a history of severe latex allergy?

1 Answers

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Dermatology · Wake Forest University

I don't have a lot of data to go on. On the one hand, I would be comfortable, as I doubt there would be any problem as long as the patient didn't touch the latex in the needle cover. But since we have many products without latex, perhaps it would be prudent to use those first. If other options were ...

How do you approach PJP prophylaxis in patients with rheumatic disease on corticosteroids?

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Rheumatology · Duke University Medical Center

Here is a graphic I made covering PJP Prophylaxis with Dr. @Dr. First Last if anyone is interested! As noted, one can check absolute lymphocyte count (ALC) or CD4 count as factors to further risk stratify as well.

How do you approach the management of poorly controlled migraines during pregnancy?

3 Answers

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Neurology · ProHealth Physicians Headache Neurology

This is an excellent question and area of frequent discussion. You can start with Lidocaine nerve blocks: occipital, supra-orbital, and temporal. Sometimes, just IV fluids will help for acute migraines. Other options include Reglan, caffeine, and APAP. If in the second trimester, I will do steroid t...

What is your typical approach to the use of beta blockers in the setting of recent cocaine use amongst patients presenting with cocaine-related MI, arrhythmias, or new-onset heart failure?

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Cardiology · Yale University School of Medicine

I favor using or continuing non-selective beta-blockers in patients presenting with acute cardiac manifestations of recent cocaine use. My preferred agent in this setting is carvedilol.

What is the youngest age and dose that you would consider for oral minoxidil?

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Dermatology · Johns Hopkins Timeshare Practice

I would consider prescribing oral minoxidil for children as young as 2 years old, but only if the condition is severe and does not respond to topical therapy.

What is your go-to strategy for non-opioid management of chronic low back pain in patients with limited access to physical therapy or behavioral health?

1 Answers

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Neurology · Nerve and Pain Institute

The short answer is that if pain fails to improve after three months of conservative management, patients should be referred to a board-certified pain physician for further evaluation and treatment. The long answer is that chronic pain management is a highly complex, multidisciplinary field that can...

What is your go-to strategy for non-opioid management of chronic low back pain in patients with limited access to physical therapy or behavioral health?

1 Answers

Mednet Member
Mednet Member
Neurology · Nerve and Pain Institute

The short answer is that if pain fails to improve after three months of conservative management, patients should be referred to a board-certified pain physician for further evaluation and treatment. The long answer is that chronic pain management is a highly complex, multidisciplinary field that can...

Do normal methylmalonic acid levels absolutely rule out vitamin B12 deficiency?

1 Answers

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Hematology · Dana-Farber Cancer Institute

An elevated MMA is a good indicator of B-12 deficiency but a normal level does not argue strongly against B-12 deficiency. Normal MMA levels have been reported in 10-25% of patients with known B-12 deficiency (B-12 levels below 100). Testing for an elevated homocysteine level might help but this tes...