Psychiatry
Expert discussions on psychopharmacology, behavioral health interventions, and psychiatric care approaches.
Recent Discussions
How will your approach to screening and diagnosis of early dementia change given newly available therapies for early Alzheimer's disease?
As it stands, it is not recommended to screen asymptomatic patients for the proteins seen in Alzheimer’s disease outside of clinical trials (i.e., AHEAD 3-45). However, with the emergence of new treatment options in the clinic, I foresee an influx of patients with cognitive symptoms who need a preci...
Where in your treatment approach to fibromyalgia will you recommend sublingual cyclobenzaprine?
The choice of medication for any given patient is based on a lot of factors and, realistically, is often highly dependent on affordability and insurance coverage across different pharmacy plans. Despite other FDA-approved options, oral cyclobenzaprine is usually the medication I reach for first with...
How do you decide when and how often to reach out to patients with serious mental illness who are disengaging from care due to psychosocial stressors?
Outreach is always determined on a case-by-case basis, so it's difficult to give a definitive answer on this. Important factors to consider are the person's functional status, potential risk for harm without care, their decision-making ability, and the intensity of stressors. Obviously, those who ar...
How do you determine disposition when a patient presents to an outpatient psychiatry visit with recent self-injury that may require medical attention?
I agree with the responses that it has to be individualized, but if the self-injury is severe enough to warrant "medical attention" (I assume that means requiring sutures?), then in most cases that would warrant an emergency detention order in my opinion. Even in the case of borderline patients, thi...
When do you consider low-dose buprenorphine for the management of treatment resistant depression?
At doses of 0.25-2 mg, buprenorphine has potent kappa opioid receptor antagonism, and this conveys anxiolytic and antidepressant activities. It can be used in an augmentation mode with other antidepressants. See (Karp et al., PMID 25191915; Fava et al., PMID 26869247; Thase et al., PMID 31254971; Fa...
What is your approach to augmenting treatment for depressive disorders in those continuing to take a tricyclic antidepressant at baseline due to historical effectiveness?
Depends on the risk of suicidality. If there is any history or any hint of a possibility of it, I do not continue with a TCA. I would augment with a dopamine agonist. I only use TCA to help with multiple comorbidities, such as migraines, insomnia, neuropathic pain, along with depression - knowing I ...
What is your pharmacological approach to treating depressive disorders in patients who develop serotonin toxicity?
I would try bupropion. Not Auvelity, as dextromethorphan has serotonergic activity. I would want to see if they were on any medication other than psychiatric that contributed to serotonin syndrome, like tramadol, and get rid of that or replace it as needed. I would probably want to transition to a n...
How do you counsel patients who are hesitant to try behavioral therapies for insomnia instead of starting a sleep medication?
I try to be very understanding of the desire to have an easier solution to sleep difficulties, which are so common. It is challenging that our gold standard and best strategies to help people sleep better require a lot of effort on the patient's part. Starting with that validation can be very helpfu...
How do you approach requests from attorneys to complete paperwork supporting your patient’s application for long-term disability?
If the diagnosis does not support disability, I will give the attorney a call. This saves time, money, and my effort of writing a report. They may provide more collateral, or they may not use me. Either way, I am not stuck defending an untenable position. In terms of ambiguous questions, I try to be...
How do you approach firearm safety counseling for outpatients with elevated suicide risk who do not meet the criteria for involuntary psychiatric hospitalization?
I have found the framework outlined by the BulletPoints Project (created by the California Firearm Violence Research Center at UC Davis) to be very helpful. I start by asking about the patient’s goals for owning firearms. I think it is important to recognize that guns often form an important part o...