Do you continue biologics in sJIA patients who develop lung disease on anti IL-1 or anti IL-6 therapies?

It really does depend. If a child is otherwise doing well, stopping cytokine inhibitors can worsen the underlying disease precipitously, putting the child at risk. More often than not, in my experience, at the time that lung disease is discovered, the treatments are not controlling the underlying di...

As was mentioned in the debate, "it depends." I also exclusively use weekly SC methotrexate and anakinra to treat sJIA. I likely would not stop anakinra unless there was a clear allergic reaction to the injections. If MAS is an issue, as it often is with sJIA lung disease, then all the more reason t...