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Do you recommend GLP-1s for antispychotic induced weight gain?

2 Answers
Mednet Member
Mednet Member
Psychiatry · Perelman School of Medicine, University of Pennsylvania

When antipsychotic induced weight gain causes obesity (BMI>30), I recommend a trial of tirzepatide or semaglutide. I have observed the typical benefits in my patients, including decreases in lipids, lower HgbA1c, lower BPs, improved mobility, and loss of 10-20% of body weight over 6 months. Expense ...

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Mednet Member
Mednet Member
Psychiatry · Oregon Health Sciences University

I would generally refer to the PCP for this discussion and a prescription, but I would always bring up GLP-1s as an option to consider. Of course, I would recommend first increasing physical activity, Mediterranean diet strategies, and sleep hygiene. But we do make patients' jobs harder with our med...

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