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Do you switch from 0.15 mg to 0.3 mg epinephrine at 55 lbs or 66 lbs?

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Mednet Member
Mednet Member
Allergy & Immunology · University of Chicago

Dr. @Dr. First Last, thank you for posting this question. I see variances in practice among both allergy and primary care practices on when a patient is prescribed the 0.3mg dose of epinephrine. Our practice is to switch patients to 0.3mg when they are 25 kg to prevent underdosing and inadequate res...

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Mednet Member
Mednet Member
Allergy & Immunology · University of Washington School of Medicine

The rationale for making this switch is that 0.15 mg epinephrine significantly under treats a 25 kg child (who would receive 0.25 mg in the ER setting), and that a slightly higher dose of 0.30 mg is typically well tolerated. References: Sicherer & Simons, PMID 17332221, and Brayn et al., PMID 281837...

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Do you switch from 0.15 mg to 0.3 mg epinephrine at 55 lbs or 66 lbs? | Mednet