Do you use an alternative dosing regimen for CDK4/6 inhibitor in patient with benign ethnic leukopenia?

It is known that patients of african descent have a lower white blood counts (Ethnic Neutropenia). Despite the lower WBC and Neutrophil count, there is no evidence of increased risk of infection. In this setting i usually do not lower the dose, but set a lower cut-point for dose change, or only chan...