Do you use MRSA nares PCR to influence antibiotic selection for non-respiratory infections?

BLUF: Yes, I use a MRSA nares PCR for early de-escalation in the stable patient with a non-purulent, non-respiratory infection.

Mergenhagen et al., PMID 31573026 retrospectively examined nearly half a million clinical cultures and compared them to MRSA nares results. Among all infections, the NPVs w...

I answered this question, I believe, last September. I have re-reviewed the literature. There is not a single RCT demonstrating that empiric MRSA coverage can be safely discontinued on the basis of a negative nasal MRSA screen.

As discussed previously, the VA Clinical Infectious Diseases study had a ...