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How do you approach further evaluation in a patient presenting with fatigue and arthralgias who is found to have low C3 and C4 levels, but has a negative ANA and otherwise unremarkable workup for SLE, with overall low clinical suspicion for active rheumatologic disease?

How do you approach further evaluation in a patient presenting with fatigue and arthralgias who is found to have low C3 and C4 levels, but has a negative ANA and otherwise unremarkable workup for SLE, with overall low clinical suspicion for active rheumatologic disease? | Mednet