How do you decide between continuing 5FU + Chemo (Oxaliplatin or Irinotecan) + Bevacizumab versus switching to maintenance 5FU + Bevacizumab in the first line setting for metastatic colon cancer?

In general, after 4-6 months of induction chemotherapy, if they experience a favorable response, I would favor maintenance chemotherapy based off several clinical trials which have shown a benefit for a maintenance approach, notably OPTIMOX and CAIRO-3. The continuation of oxaliplatin or irinotecan ...