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How do you decide between repeat resection and radiosurgery when MRI imaging suggests limited residual tumor in the cavernous sinus in patients treated for acromegaly?

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Endocrinology · Johns Hopkins Endocrinology and Pituitary Center

If residual tumor is not surgically curable, another surgery is not advisable. Given available pharmacological treatments, I do not consider XRT until I run out of medical options, particularly in young patients with intact pituitary function. Even if a patient does not respond to SRL, including pas...

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Endocrinology · Kaiser Permanente Oakland Medical Center Endocrinology

Resection of residual tumor in the cavernous sinus is difficult, and most neurosurgeons will not do it. If acromegaly is controlled on medical treatment with octreotide, which can also help reduce tumor size, repeat surgery or radiation may not be needed.

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