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How would you approach treatment for a patient with a residual disease after resection of a solitary jejunal myeloblastic sarcoma?

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Mednet Member
Radiation Oncology · Duke University Medical Center

Myeloid sarcoma (historically- chloroma or granulocytic sarcoma) is simply an extramedullary form of AML. The majority of patients who present de novo with a myeloid sarcoma will either have bone marrow involvement at diagnosis or will develop such metachronously if systemic therapy is not pursued. ...

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Mednet Member
Mednet Member
Hematology · UMass Chan Medical School

Isolated Myeloblastic sarcoma presentation is associated with a high rate of progression to AML within 1 year and is a poor prognostic factor. It tends to be associated with t(8;21) AML. I would pursue systemic treatment and even consider allo SCT if the patient is a transplant candidate, Aslam et a...

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