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In AIH/PBC overlap with both hepatitis and cholestasis, how do you determine whether incomplete biochemical response at 6–12 months reflects undertreated AIH versus inadequately controlled cholestasis?

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Mednet Member
Mednet Member
Hepatology · University Of Colorado Hospital Authority

Overlap can be very challenging to treat. In this situation, it is reasonable to perform a repeat liver biopsy. If autoimmune hepatitis remains active, it would increase the IS.

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In AIH/PBC overlap with both hepatitis and cholestasis, how do you determine whether incomplete biochemical response at 6–12 months reflects undertreated AIH versus inadequately controlled cholestasis? | Mednet