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In cirrhosis with suspected HRS-AKI and baseline CKD or chronically elevated creatinine, how do you define a clinically meaningful ‘improvement’ during an albumin trial (over 24–48 hours) to distinguish HRS-AKI from volume-responsive AKI?

1 Answers
Mednet Member
Mednet Member
Hepatology · University of Toronto

If the acute rise in serum creatinine returns to the pre-AKI level, the patient has volume-responsive AKI.

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