Is proximal duodenal adenocarcinoma (above the ampulla of Vater) considered biologically similar to colon adenocarcinoma or gastric cancer?
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2 Answers
Mednet Member
Medical Oncology · Baylor College of Medicine
There are differences in their biology, however, duodenal cancers are treated with CRC regimens.
Mednet Member
Medical Oncology · Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center
Gene expression analyses support the idea that the GI tract is a continuous spectrum. Organs that are more proximal along this spectrum are likely more similar to each other than organs that are more distal from each other along this spectrum. Therefore, it seems reasonable to consider proximal du...