Is thyroglobulin typically elevated in patients with Hashimoto's thyroiditis on adequate thyroid hormone replacement?

Any thyroid condition where there is an enlarged goiter or stimulated cell by a high TSH will increase the thyroglobulin levels. A long time ago, when I was a fellow, Tg's were measured to correspond with MNG growth. In those situations, I have seen levels in the 1,000's, and a large nodule can have...

Thyroglobulin is a protein made both by normal thyroid tissue and by most differentiated thyroid cancers. In someone with an intact thyroid, this value can be very challenging to interpret and use clinically. With that said, yes, inflammatory events in the thyroid can raise thyroglobulin. I would fi...