Should a trial of cenobamate (Xcopri) be required before referring a patient for epilepsy surgery?

First, I would like to declare my conflict of interest that I am a speaker for Xcopri/SK Life. That being said, I only speak for things I truly use and believe in.

My general teaching to learners is this (not saying there cannot be exceptions): I would not use Xcopri first line because there are bet...

Thank you for bringing forward this important and timely topic. While perspectives may reasonably differ regarding the optimal role and timing of additional antiseizure medication trials in individual patients, there is broad agreement within the epileptology community that favorable surgical candid...

It’s not cenobamate vs. surgery. It can be both. I start all candidates for surgery at the time of their Video-EEG if they are not taking the medication already. If and when they become seizure-free, I use that period to prepare them for a life without seizures. If they are not working, I refer them...