Should we be shrinking rectal cancer fields?

I think this is a good point. However, I think we need to consider the nuances of the question. First PROSPECT included: patients that "had cT2N+, cT3N-, cT3N+ rectal cancers deemed appropriate for neoadjuvant therapy prior to low anterior resection with TME. Patients with distal, T4 tumors, threate...

Definitely agree with all the points made above for and against shrinking fields.

I believe it's appropriate to think about shrinking fields especially with publications of OPERA results (Gerard et al., PMID 36801007), that with the addition of brachytherapy, one can achieve a significantly higher c...