What is the maximum dose that you would give to residual unresectable gross disease in the axilla in the setting of recurrent breast cancer s/p ALND?

The FAST-Forward boost trial will be informative here, and I would recommend reading the protocol, because one can consider using the standard arm now, which is 40 Gy to the breast (and nodes, when RNI is indicated), and a 48 Gy boost, all in 15 fractions. This dose is recognizable as the breast boo...

Good question. For both supraclavicular and axillary gross nodes, the issues are quite similar; i.e., the brachial plexus makes it challenging to give a high enough dose to control gross disease. A few thoughts:

1. For gross disease, it is always good to consider adding concurrent chemo as a sensitize...

Based on the size of the node, an EQD2 of 60 to 66 Gy.