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What systemic chemotherapy do you prefer with concurrent radiation therapy in the neoadjuvant setting for early stage rectal cancer?

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Mednet Member
Mednet Member
Medical Oncology · University of Texas MD Anderson Cancer Center

In this setting, I always prefer capecitabine for the sake of patient convenience. If there is a reason I can't use it (e.g. renal insufficiency, poor compliance with oral medications), I opt for infusional 5-FU. I would only consider bolus 5-FU if the patient experienced coronary vasospasm with cap...

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