What tools or disease activity markers do you find most useful in tracking disease activity in Sjogren's patients?

The frequency of monitoring depends on the patient’s phenotype. For example, in patients with evidence of immunologic activity at baseline, such as B-cell hyperactivity, hypocomplementemia, or cryoglobulinemia, labs should generally be repeated every 3 to 6 months, particularly if they have active e...

This would vary depending on the phenotype of the patient and which systemic domains were affected at a given point in time. The only validated disease activity instrument accepted by regulatory agencies at present is the ESSDAI (Seror et al., PMID 31236580), and the patient-reported outcome (ESSPRI...