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What treatments do you consider for cholinergic urticaria refractory to high dose H1 blockers and omalizumab?

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Allergy & Immunology · Johns Hopkins Asthma And Allergy Center

Generally, my initial approach to cholinergic urticaria (CholU) is the same for chronic spontaneous urticaria and other forms of chronic inducible urticaria [1]. Most patients with antihistamine-refractory cholinergic urticaria (CholU) will respond to omalizumab 300 mg monthly. Those individuals wit...

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What treatments do you consider for cholinergic urticaria refractory to high dose H1 blockers and omalizumab? | Mednet