What would be your choice and duration of adjuvant therapy for a perforated MSI-H stage II (T4N0) colon cancer?

There are no data of which I am aware which directly address this situation. Although patients with stage II MSI-H tumors generally have an extremely favorable prognosis, the perforation is worrisome. I would not be opposed to giving six months of adjuvant FOLFOX in this setting as long as the patie...