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When do you use olanzapine for acute migraine treatment?

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Mednet Member
Mednet Member
Neurology · UCLA

Although off-label and not included in guidelines, olanzapine can be helpful for migraine attacks in the ER and even for prevention in chronic migraine that has failed all other treatments. 10 mg is usually given IM and 2.5 or 5 mg IV. The MOA is probably as a dopamine antagonist and it is often use...

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Mednet Member
Mednet Member
Neurology · Greater Boston Headache Center at Boston Advanced Medicine

No, I don't. I only use migraine-specific medications. As far as I am concerned, that is the standard of care. Ergots, triptans, and gepants abortively, and CGRP-antibodies and gepants preventively.

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