When should you consider adding clonidine to an antihypertensive regimen for patients with advanced CKD?

Clonidine patch is useful in severely uncontrolled hypertension. In patients with CKD, not responding to conventional medications - like calcium blockers. Though the side effect profile is not great, it is less expensive and practical.

Resistant Hypertension is often encountered in Cardiology and Nephrology clinics. It becomes challenging when the patient has concomitant chronic kidney disease.

It is important to know and use clonidine tabs or patches in these populations safely.